The impact of cognitive behavioral therapy on disease uncertainty, stressful life events, quality of life, anxiety, and depression in glioma patients undergoing chemotherapy: a quasi-experimental study.

in BMC psychiatry by Xiaonan Liu, Xiaolei Qi, Dandong Fang, Shubing Feng, Jing Chen, Xue Li, Jiajia Dang, Lin Wu

TLDR

  • The study found that cognitive behavioral therapy (CBT) can significantly improve disease uncertainty, stressful life events, and quality of life in glioma patients undergoing chemotherapy.
  • The study suggests that CBT can be an effective addition to standard nursing care for glioma patients.

Abstract

To investigate the effect of cognitive behavioral therapy on disease uncertainty and stressful life events in glioma patients undergoing chemotherapy. This quasi-experimental study enrolled 90 glioma patients from Sanmenxia Central Hospital between January and December 2021. Patients were divided into an intervention group (n = 45) or a control group (n = 45). The intervention group received cognitive behavioral therapy provided by nurses, while the control group received routine nursing care. Pre- and post-intervention assessments were conducted using the Mishel uncertainty in illness scale (MUIS), life events scale (LES), self-rating anxiety scale (SAS), self-rating depression scale (SDS), and quality of life scale (WHOQOL-BREF). After four cycles of chemotherapy, the study group demonstrated a statistically significant decrease in MUIS and LES scores compared to the control group (p < 0.05). The study group showed significantly lower SAS and SDS scores than the control group (p < 0.05). Finally, the study group reported significantly higher WHOQOL-BREF scores than the control group (p < 0.05). The study revealed that the group that received CBT showed significant improvements in the psychological well-being of glioma patients undergoing chemotherapy. These findings suggest that incorporating CBT into standard nursing care can effectively improve the psychological well-being and quality of life of glioma patients during chemotherapy.

Overview

  • The study investigated the effect of cognitive behavioral therapy (CBT) on disease uncertainty and stressful life events in glioma patients undergoing chemotherapy.
  • The study was a quasi-experimental design that enrolled 90 glioma patients and divided them into an intervention group receiving CBT and a control group receiving routine nursing care.
  • The study aimed to determine the effect of CBT on psychological well-being and quality of life in glioma patients undergoing chemotherapy.

Comparative Analysis & Findings

  • The study found that the intervention group that received CBT demonstrated statistically significant decreases in disease uncertainty and stressful life events compared to the control group.
  • The intervention group showed significantly lower anxiety and depression scores compared to the control group.
  • The intervention group reported a significant improvement in quality of life compared to the control group.

Implications and Future Directions

  • The study suggests that incorporating CBT into standard nursing care can effectively improve the psychological well-being and quality of life of glioma patients during chemotherapy.
  • Future studies could explore the long-term effects of CBT on glioma patients' psychological well-being and quality of life.
  • The study highlights the importance of providing supportive interventions, such as CBT, to glioma patients undergoing chemotherapy to improve their overall outcomes.
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