Abstract
HOXC13 antisense RNA (HOXC13-AS, also known as HOXC-AS5) is a long non-coding RNA that is expressed abnormally in various types of tumors and is closely related to clinical staging, clinical pathological features, and patient survival. HOXC13-AS is involved in the occurrence and development of tumors, affecting cell proliferation, migration, invasion, epithelial-mesenchymal transition, and tumor growth. This review summarizes the clinical significance of HOXC13-AS as a biomarker for human tumor diagnosis and prognosis and outlines the function and molecular regulation mechanism of HOXC13-AS in various types of cancer, including nasopharyngeal carcinoma, breast cancer, oral squamous cell carcinoma, glioma, and cervical cancer. Overall, this review emphasizes the potential of HOXC13-AS as a human tumor predictive biomarker and therapeutic target, paving the way for its clinical application.
Overview
- The study focuses on the clinical significance of HOXC13-AS as a biomarker for human tumor diagnosis and prognosis.
- HOXC13-AS is a long non-coding RNA that is abnormally expressed in various types of tumors and is closely related to clinical staging, clinical pathological features, and patient survival.
- The study aims to summarize the function and molecular regulation mechanism of HOXC13-AS in various types of cancer and its potential as a predictive biomarker and therapeutic target.
Comparative Analysis & Findings
- HOXC13-AS is involved in the occurrence and development of tumors, affecting cell proliferation, migration, invasion, epithelial-mesenchymal transition, and tumor growth.
- The expression of HOXC13-AS is abnormally regulated in various types of cancer, including nasopharyngeal carcinoma, breast cancer, oral squamous cell carcinoma, glioma, and cervical cancer.
- The study highlights the potential of HOXC13-AS as a biomarker for human tumor diagnosis and prognosis, and outlines its function and molecular regulation mechanism in various types of cancer.
Implications and Future Directions
- The study emphasizes the potential of HOXC13-AS as a human tumor predictive biomarker and therapeutic target, paving the way for its clinical application.
- Future studies should investigate the molecular regulation mechanism of HOXC13-AS in various types of cancer and its potential therapeutic applications.
- The development of HOXC13-AS-based diagnostic and therapeutic methods could lead to improved treatment outcomes and patient survival rates in various types of cancer.