Nanotheranostics: The Fabrication of Theranostics with Nanoparticles and their Application to Treat the Neurological Disorders.

in Recent patents on nanotechnology by Astha Singh, Aakriti Patel, Hema Chaudhary, Kiran Yadav, Neha Minocha

TLDR

  • This review provides a comprehensive overview of nanotheranostics and its potential for treating neurological disorders, highlighting its benefits, challenges, and future directions.
  • Nanotheranostics has the potential to revolutionize the treatment of neurological disorders by providing personalized medicine and enhancing drug efficacy and safety.

Abstract

Theranostics is a method that focuses on providing patient-centred care and is evolving as a targeted, safe, and effective pharmacotherapy. Nanotheranostics combines diagnosis and therapeutic modalities that bridge traditional treatment and personalised medicine. Theranostics provides novel ideas for nanotechnology. This review describes the current state of nanotechnology-based therapies used to treat neurological illnesses. Some patents on theranostics are also discussed in this review. This study aims to provide a more comprehensive review of the diagnosis and therapeutic properties of nanotheranostics, the present state of nanotechnology-based treatment of neurological disorders, and the future potential of theranostics. The phrase "theranostics" refers to a treatment strategy that integrates therapeutics and diagnostics to monitor treatment response and enhance drug efficacy and safety. Theranostics is a crucial component of personalised medicine and calls for significant advancements in predictive medicine. The term "theranostics" refers to a diagnosis that screens patients for potential adverse drug reactions and targets drug delivery depending on the test results. Theranostics treats neurological disorders (like brain tumours (glioma), Parkinson's disease, Alzheimer's disease, and neurovascular diseases). Many review articles on Google Scholar, PubMed, Google Patents, and Scopus were used to gather information for this review. Data acquired from many sources was compiled in this review to provide more information on theranostics. The role of various nanocarrier systems as theranostic agents for neurological illnesses and the fabrication of nanomaterials for theranostics are discussed in this article after evaluating a substantial number of review articles. The distinctive intrinsic features of nanoparticles make them useful for functionalization and imaging. Theranostics in nuclear medicine include diagnostic imaging and therapy using the same molecule that is radiolabeled differently or the same medication at various doses. It is possible to determine if a patient will benefit from a given treatment by visualising potential targets. Targeted nuclear therapy has been shown to be beneficial in patients if chosen carefully and has a good safety profile.

Overview

  • The study aims to provide a comprehensive review of nanotheranostics, focusing on the diagnosis and therapeutic properties of nanotheranostics, the present state of nanotechnology-based treatment of neurological disorders, and the future potential of theranostics.
  • The study evaluates the role of various nanocarrier systems as theranostic agents for neurological illnesses and discusses the fabrication of nanomaterials for theranostics, highlighting the benefits of using nanoparticles with their intrinsic features.
  • The study also touches on theranostics in nuclear medicine, discussing the possibilities of imaging and therapy using the same molecule with different labels or at various doses.

Comparative Analysis & Findings

  • The analysis compares the effectiveness of different nanocarrier systems as theranostic agents for neurological illnesses, highlighting the benefits and challenges of each system.
  • The study finds that targeted nuclear therapy has shown promising results in patients, particularly when chosen carefully and with a good safety profile.
  • The findings suggest that theranostics has the potential to revolutionize the treatment of neurological disorders by providing personalized medicine and enhancing drug efficacy and safety.

Implications and Future Directions

  • The study's findings have significant implications for the development of personalized medicine, particularly in the treatment of neurological disorders, and highlight the need for further research to enhance drug efficacy and safety.
  • Future directions may include exploring new nanocarrier systems and nanomaterials for theranostics, as well as investigating the potential of theranostics in other medical fields.
  • The study also calls for significant advancements in predictive medicine to ensure the successful implementation of theranostics.
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