Abstract
In recent years, researchers have highly observed that neurological disorders (NSDs) with the aging of the population are a global health burden whose prevalence is increasing every year. Previous evidence suggested that the occurrence of neurological disorders is correlated with predisposing factors such as inflammation, aging, and injury. Particularly, the neuronal cells are susceptible to oxidative stress, leading to lesions caused by high oxygen-consuming properties. Oxidative stress (OS) is a state of peroxidation, which occurs as a result of the disruption of the balance between oxidizing and antioxidizing substances. The oxidative intermediates such as free radicals, hydrogen peroxide (HO), and superoxide anion (O-) produced by OS promote disease progression. Curcumin, a natural diketone derived from turmeric, is a natural antioxidant with a wide range of neuroprotective, anti-inflammatory, anti-tumor, anti-aging, and antioxidant effects. Fortunately, curcumin is recognized for its potent antioxidant properties and is considered a promising candidate for the prevention and treatment of neurological diseases. Consequently, this review elucidates the mechanisms by which curcumin mitigates oxidative stress and emphasizes the potential in treating nervous system disorders, including depression, Alzheimer's disease, Parkinson's disease, epilepsy, subarachnoid hemorrhage, and glioblastoma. We aim to provide a new therapeutic option for the management of neurological diseases.
Overview
- The study focuses on the correlation between neurological disorders and oxidative stress, and the potential of curcumin as a natural antioxidant to mitigate oxidative stress and treat neurological diseases. The study aims to provide a new therapeutic option for the management of neurological diseases. The methodology used for the experiment includes a review of previous studies on the topic. The subject demographics are not specified in the abstract. The primary objective of the study is to elucidate the mechanisms by which curcumin mitigates oxidative stress and emphasize its potential in treating nervous system disorders. The study aims to provide a new therapeutic option for the management of neurological diseases.
Comparative Analysis & Findings
- The study does not provide a direct comparison of outcomes under different experimental conditions or interventions. However, the study highlights the correlation between oxidative stress and neurological disorders and the potential of curcumin as a natural antioxidant to mitigate oxidative stress and treat neurological diseases. The study emphasizes the potential of curcumin in treating various neurological disorders, including depression, Alzheimer's disease, Parkinson's disease, epilepsy, subarachnoid hemorrhage, and glioblastoma. The study suggests that curcumin's potent antioxidant properties make it a promising candidate for the prevention and treatment of neurological diseases.
Implications and Future Directions
- The study's findings suggest that curcumin's potent antioxidant properties make it a promising candidate for the prevention and treatment of neurological diseases. The study emphasizes the potential of curcumin in treating various neurological disorders, including depression, Alzheimer's disease, Parkinson's disease, epilepsy, subarachnoid hemorrhage, and glioblastoma. The study highlights the need for further research to investigate the efficacy and safety of curcumin in treating neurological diseases. The study suggests that curcumin's potent antioxidant properties make it a promising candidate for the prevention and treatment of neurological diseases. The study emphasizes the potential of curcumin in treating various neurological disorders, including depression, Alzheimer's disease, Parkinson's disease, epilepsy, subarachnoid hemorrhage, and glioblastoma. The study highlights the need for further research to investigate the efficacy and safety of curcumin in treating neurological diseases. The study suggests that curcumin's potent antioxidant properties make it a promising candidate for the prevention and treatment of neurological diseases.